Laboratory diagnostics of venereal diseases. Treatment of syphilis.

1. Syphilis is caused by:

1) Blue-pus bacillus;

2) Streptococcus;

3) Staphylococcus;

4) Escherichia coli;

5) Treponema pallidum.*

2. The basic signs of syphilis are:

1) Chancroid;

2) Hard chancre;*

3) Polyadenitis;*

4) Regional scleradenitis;*

5) Negative serum reactions;

6) Positive serum reactions;*

7) Syphilids.*

3. The most reliable method of diagnostics of tertiary syphilis is:

1) Examination of material taken from the bottom of ulcer;

2) Examination of neurolymph;

3) Blood examination (Wassermann's reaction);

4) T. pallidum immobilization test;*

5) Precipitin reactions.

4. The most specific serological reaction for syphilis is:

1) The fluorescence test;

2) T. pallidum immobilization test;*

3) Wassermann's reaction with the treponemal antigen;

4) Wassermann's reaction with the cardiolipin antigen;

5) Microreaction.

5. Who must be inspected (serological test of blood) in case of suspicion of congenial syphilis?

1) Father;

2) Mother;*

3) Child;*

4) Brothers and sisters of child;

5) Mother’s relatives;

6) Father’s relatives.

6. Select multiplicity and terms of examination of pregnant for syphilis (Wassermann's reaction):

1) Examination is carried out not less than twice, during the first and second periods of pregnancy;*

2) In each 2 monthes;

3) Single examination before childbirth;*

4) Single examination in the II trimester of pregnancy.

7. A 22 years old woman complains of appearance of ulcer on a large vulvar lips. The subjective feelings are absent. In anamnesis – there was a sexual contact with a little known man month ago. What examinations must be done first of all for determination of diagnosis?

1) Examination for T. pallidum;*

2) Examination for gonococci;

3) Examination for trichomonads;

4) Examination for fungi;

5) Examination for Chlamydia.

8. The serological reactions of pregnant in the first and second half of pregnancy is conducted in:

1) Skin and venereal dispensary;

2) Maternity ward;

3) Gynaecological department;

4) Maternity welfare centre;*

5) Out-patients' clinic.

9. After contact with a syphilitic patient Wassermann's reaction becomes positive in:

1) 1 week;

2) 2 weeks;

3) 4-5 weeks;

4) 6-8 weeks;*

5) 9-10 weeks.

10. After appearance the hard chancre Wassermann's reaction becomes positive in:

1) 1 week;

2) 2 weeks;

3) 3-4 weeks;*

4) 5-6 weeks;

5) 8-9 weeks.

11. What serological reactions for syphilis can be positive in the case of the primary seronegative period of syphilis?

1) IFT;*

2) Wassermann's reaction;

3) IFT, TPI;

4) TPI;

5) Classical, serological reactions.

12. What method of diagnosing is used in everyday practice for the reveal of T. pallidum?

1) Cultivation on nutrient mediums;

2) Staining by the Romanovsky-Giemsa;

3) Staining by methylene blue;

4) Examination of native preparations in dark field illumination of the microscope;*

5) Silvering by the Morozov.

13. After an infection with syphilis, usually, the Wassermann's reaction becomes positive in:

1) 3-4 weeks;

2) 6-8 weeks;*

3) 9-12 weeks;

4) 3-4 months;

5) 2-4 years.

14. What physiological secretion and excreta can be contagious in syphilis?

1) Saliva;*

2) Sweat;

3) Urine;

4) Milk;*

5) Sperm.*

15. What serological reactions for syphilis can be positive in the case of the primary seropositive period of syphilis?

1) Express-method;*

2) IFT;*

3) Wassermann's reaction;*

4) TPI;

5) Classical, serological reactions.*

16. What serological reactions can be positive in the case of secondary recurrent syphilis?

1) Express-method;*

2) IFT;*

3) Wassermann's reaction;*

4) TPI;*

5) IFT, TPI.*

17. The positive results of the followings tests are needed for diagnosis of primary seropositive period of syphilis with typical clinical picture:

1) IFT;

2) TPI;

3) Microreaction;

4) Wassermann's reaction.*

18. What serological reactions will be positive in the case of secondary early syphilis?

1) Express-method;*

2) IFT;*

3) Wassermann's reaction;*

4) IFT, TPI;*

5) All of reactions are negative.

19. The diagnosis of syphilis always is based on signs:

1) Clinical manifestation;

2) Information of anamnesis;

3) Laboratory examinations;

4) All above-listed.*

20. The laboratory methods of diagnostics of syphilis are distinguished:

1) Detection of causative agent of disease in lesions;

2) Serological reactions for syphilis;

3) Microprecipitation test;

4) Immunofluorescence test;

5) T. pallidum immobilization test;

6) All above-listed.*

21. The T. pallidum immobilization test is used with a purpose for:

1) Making the diagnosis of primary syphilis;

2) Making the diagnosis of early syphilis;

3) Making the diagnosis of latent syphilis;*

4) Appraising the efficacy of antisyphilitic therapy;

5) Taking off the record completely cured patient.

22. What reaction is used for express-diagnostics of syphilis?

1) RW;

2) Microprecipitation test;*

3) IFT;

4) TPI.

23. Criteria of cure of syphilis is considered:

1) Quality of the conducted treatment;

2) Data of clinical inspection (skin, mucous membranes, internal organs, nervous system, organs of sense);

3) Data of laboratory examinations (CSR, IFT, TPI);

4) All above-listed.*

24. Wassermann's reaction is based on:

1) Hematolysis;*

2) Yellow-green fluorescence of T. pallidum;

3) Recognition of false positive non-specific results of standard serum reactions.

25. The basic specific antisyphilitic medicines are considered all from following, except for:

1) Penicillin;

2) Bicillin;

3) Retarpen;

4) Extencilline;

5) Tetracycline.*

26. Nonspecific medicines for treatment of syphilis are considered:

1) Immune preparations (Thymogen, Thymalin, Laferon, Methyluracil);*

2) The group of stimulating preparations (Pyrorenal, Aloe, FIBS, Plasmol, extract of placenta and others like that);*

3) Vitamin therapy;*

4) The group of reserve.

27. What can be taken excretions for laboratory examination from?

1) Lesions;*

2) Aspirate of a regional lymph node;*

3) Serum;*

4) Neurolymph;*

5) Scales from papular shyphilids.

28. Criteria of cure of syphilis are:

1) Patients who have completed antisyphilitic treatment are kept under dispensary care;*

2) The patient visits the physician once in three months during the first two years;*

3) The patient visits the physician once in six months during the third year for medical examination and serological tests and then they are taken off the record;*

4) During 3 years;*

5) During 5 years.

29. Basic medicines for treatment of patients with syphilis are:

1) Preparations of penicillin;*

2) Preparations of tetracycline;

3) Preparations of erythromycin;

4) Macrolids.

30. What is characteristic for latent early syphilis with sharply positive Wassermann's reaction:

1) Low titre of reaginic antibodies;

2) High titre of reaginic antibodies;*

3) The titre of reaginic antibodies does not have any value.

31. Such complications can be during the treatment of syphilis with penicillin except for:

1) Anaphylactic shock;

2) Toxicodermia;

3) Hives;

4) Candidiasis;

5) Alopecia.*

32. The second recurrent syphilis is suspected in a patient. CSR are weakly positive. It is necessary to apply the followings reactions:

1) Kolmer's test;

2) The fluorescence test;

3) T. pallidum immobilization test;*

4) Microreaction;

5) Wassermann's reaction with the cardiolipin antigen.

33. Patients with a gonorrhoea with the unrevealed source of infection, but having a permanent address and work:

1) Preventive antisyphilitic treatment is conducted;

2) Preventive antisyphilitic treatment is not conducted;

3) Clinical and serological control is carried out during 3 months;*

4) Clinical and serological control is carried out during 6 months;

5) Right 2) and 3).

LESSON 23

Дата добавления: 2015-11-13