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Collagenoses. Lupus erythematosus. Sclerodermia. Etiology. Pathogenesis. Clinical features. Diagnostics. Treatment. Prevention.

Anatomy, histology and physiology of the normal skin. Histomorphological changes in the skin. | Morphology of primary and secondary skin lesions. | Psoriasis. Lichen ruber planus. Etiology. Pathogenesis. Clinical features. Diagnostics. Treatment. Prevention. | Scabies. Pediculosis. Etiology. Pathogenesis. Clinical features. Diagnostics. Treatment. Prevention. | Diseases due to virus infection. Etiology. Pathogenesis. Classification. Clinical features. Diagnostics. Treatment. Prevention. | Pyodermia. Etiology. Pathogenesis. Clinical features. Diagnostics. Treatment. Prevention. | Keratomycoses. Candidiasis. Clinical features. Diagnostics. Treatment. Prevention. Classification of mycoses. Laboratory diagnostics of mycoses | Dermatitis. Toxicodermia. Etiology. Pathogenesis. Classification. Clinical features. Diagnostics. Treatment. Prevention. | Eczema. Etiology, Pathogenesis. Classification. Clinical features. Diagnostics. Treatment. Prevention. | Bullous dermatoses. Erytema exudativum multiforme. Etiology. Pathogenesis. Clinical features. Diagnostics. Treatment. |


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  7. Clinical Manifestations and Pathogenesis

1. It is considered the basic theory of etiology of lupus erythematosus is:

1) Infectious;

2) Parasitic;

3) Allergic;

4) Autoimmune.*

2. What lesions are characteristic for chronic lupus erythematosus?

1) Crusts;

2) Maculae;*

3) Atrophy;*

4) Excoriations.

3. What lesions are characteristic for chronic lupus erythematosus?

1) Maculae;*

2) Lichenification;

3) Scales;*

4) Excoriations.

4. What lesions are characteristic for chronic lupus erythematosus?

1) Scars;

2) Atrophy;*

3) Crusts;

4) Erosion.

5. What lesions are characteristic for chronic lupus erythematosus?

1) Scales;*

2) Maculae;*

3) Nodule;

4) Ulcer.

6. What lesions are characteristic for scleroderma?

1) Maculae;*

2) Pustules;

3) Atrophy;*

4) Excoriations.

7. What lesions are characteristic for scleroderma?

1) Atrophy;*

2) Maculae;*

3) Papules;

4) Fissures.

8. What clinical forms of chronic lupus erythematosus are distinguished?

1) Discoid;*

2) Disseminated;*

3) Foliaceous;

4) Verrucous.

9. What clinical forms of chronic lupus erythematosus are distinguished?

1) Disseminated;*

2) Biett's erythema centrifugum;*

3) Vegetans;

4) Papulonecrotic.

10. What is the favoured localization of rash at patients with discoid variety of lupus erythematosus?

1) Face;*

2) Lower extremities;

3) Scalp;*

4) Upper extremities.

11. What histomorphological changes in epidermis cause a clinical picture at patients with chronic lupus erythematosus?

1) Follicular hyperkeratosis;*

2) Atrophy of germinative layer of epidermis;*

3) Parakeratosis;

4) Spongiosis.

12. Choose diagnostic symptoms, characteristic for discoid lupus erythematosus:

1) Besnier-Meshchersky's sign;*

2) The “ladies heel” sign;*

3) Nikolsky's sign;

4) Auspitz' sign.

13. What are the clinical signs of Biett's erythema centrifugum?

1) Erythema;*

2) Scales;

3) Atrophy;

4) Pigmentation.

14. What are the basic clinical signs of acute form of systemiclupus erythematosus?

1) The appearance erythema as a butterfly;*

2) Endocarditis;*

3) Polyarthritis;*

4) Leucocytosis.

15. What are the basic clinical signs of acute form of systemiclupus erythematosus?

1) Polyneuritis;

2) Haemorrhagic rash;*

3) Thrombocytosis;

4) Thrombopenia.*

16. What are the basic clinical signs of acute form of systemiclupus erythematosus?

1) Pericarditis;*

2) Haemolytic anemia;*

3) Proteinuria;*

4) Tubercles.

17. What drugs it is necessary to prescribe for treatment of chronic lupus erythematosus?

1) Delagil;*

2) Penicillin;

3) Nizoral;

4) Griseofulvin.

18. For treatment of chronic lupus erythematosus such vitamins mainly are applied:

1) C;

2) РР;*

3) В12;*

4) В1.

19. For external treatment of chronic lupus erythematosus such ointments are applied:

1) Corticosteroid;*

2) Antimycotic;

3) Vitaminous;

4) Antiparasitic.

20. What drugs are prescribed for treatment of acute systemiclupus erythematosus?

1) Prednisolone;*

2) Delagil;*

3) Methotrexate;*

4) Nizoral.

21. For treatment of systemiclupus erythematosus such vitamins mainly are applied:

1) С;

2) В12;*

3) В6;

4) РР.*

22. For external treatment of chronic lupus erythematosus such ointments are applied:

1) Antiparasitic;

2) Antimycotic;

3) Corticosteroid;*

4) Vitaminous.

23. What clinical forms of scleroderma are distinguished?

1) Seborrhoicus;

2) Plaque;

3) Linear;*

4) Systemic.*

24. What form of scleroderma occurs more frequent than all in child's age?

1) Discoid;

2) Linear;*

3) Erythrodermic;

4) Systemic.

25. What pathological condition contributing to the occurrence of scleroderma?

1) Disturbance of synthesis of collagen;*

2) Disturbance of exchange of collagen;*

3) Disturbance of microcirculation;*

4) Defects of the immune system.*

26. What are the basic initiating agents of occurrence of scleroderma?

1) Chronic infection;*

2) Endocrine dysfunction;*

3) Stresses;*

4) Overcooling.*

27. What stages are distinguished in the development of scleroderma?

1) Edema;*

2) Erythema;

3) Atrophy;*

4) Hardening.*

28. The chronic scleroderma is treated with:

1) Penicillin;*

2) Streptomycin;

3) Lydase;*

4) Aloe.*

29. The chronic scleroderma is treated with:

1) Ultrasonics;*

2) Iontophoresis;*

3) Application of paraffin;*

4) X-ray therapy.

30. What ointments are used for external treatment scleroderma?

1) Antiparasitic;

2) Vitaminous;

3) Corticosteroid;*

4) Antimycotic.

31. What organs and systems are involved in systemic scleroderma?

1) Skin;*

2) Esophagus;*

3) Urinary bladder;

4) Heart.*

32. The systemic scleroderma is treated with:

1) Streptomycin;

2) Penicillin;*

3) Lydase;*

4) Prednisolone.*

33. The systemic scleroderma is treated with:

1) Cycloferon;*

2) Gentamycin;

3) Methotrexate;*

4) Penicillin.*

34. What characteristic symptom of lupus erythematosus are distinguished?

1) Depigmentation;

2) Wickham's striae;

3) Koebner's phenomenon;

4) Erythema;*

5) Follicular hyperkeratosis;*

6) Cicatricial atrophy.*

35. Laboratory tests in lupus erythematosus are characterized by?

1) Increase in the ESR;*

2) The discovery of LE cells;*

3) Leucopenia;*

4) Anaemia;*

5) Eosinophilia.

36. What is the favoured localization of rash at patients with discoid variety of lupus erythematosus?

1) Hands;

2) Cheeks;*

3) Nose;*

4) Shins;

5) Scalp.*

37. What clinical and laboratory tests are used for diagnostics of lupus erythematosus?

1) Besnier-Meshchersky's sign;*

2) The “ladies heel” sign;*

3) Wickham's sign;

4) Method for LE cell identification.*

38. What clinical forms of lupus erythematosus are distinguished?

1) Seborrhoicus;

2) Annular;

3) Discoid;*

4) Systemic;*

5) Osteoarticular;

6) Disseminated.*

39. What is the favoured localization of rash at patients with discoid variety of lupus erythematosus?

1) Back;

2) Face;*

3) Extremities.

40. At patients with discoid lupus erythematosus may be observed:

1) Anaemia;*

2) Leucocytosis;

3) Increase in the ESR;*

4) Leucopenia.*

41. What is the succession of the stages of lupus erythematosus?

1) Follicular hyperkeratosis; 2

2) Atrophy; 3

3) Erythema. 1

LESSON 11


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