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Dermatitis. Toxicodermia. Etiology. Pathogenesis. Classification. Clinical features. Diagnostics. Treatment. Prevention.

Anatomy, histology and physiology of the normal skin. Histomorphological changes in the skin. | Morphology of primary and secondary skin lesions. | Psoriasis. Lichen ruber planus. Etiology. Pathogenesis. Clinical features. Diagnostics. Treatment. Prevention. | Scabies. Pediculosis. Etiology. Pathogenesis. Clinical features. Diagnostics. Treatment. Prevention. | Diseases due to virus infection. Etiology. Pathogenesis. Classification. Clinical features. Diagnostics. Treatment. Prevention. | Pyodermia. Etiology. Pathogenesis. Clinical features. Diagnostics. Treatment. Prevention. | Keratomycoses. Candidiasis. Clinical features. Diagnostics. Treatment. Prevention. Classification of mycoses. Laboratory diagnostics of mycoses | Dermatomycoses. Etiology. Pathogenesis. Clinical features. Diagnostics. Treatment. Prevention. | Collagenoses. Lupus erythematosus. Sclerodermia. Etiology. Pathogenesis. Clinical features. Diagnostics. Treatment. Prevention. | Bullous dermatoses. Erytema exudativum multiforme. Etiology. Pathogenesis. Clinical features. Diagnostics. Treatment. |


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  7. Clinical Manifestations

1. Which from the following symptoms are typical for dermatitis?

1) Erythema, papulae;*

2) Vesicles;*

3) Bullae;*

4) Oozing;

5) Itch;*

6) Burning pain;*

7) Rapid resolution of the removal of the etiological factor;*

8) Persistent and protracted course;

9) Tendency to the recurrence.

2. Which from the following medicine are prescribed for treatment of allergic dermatitis?

1) Lotions;*

2) Antihistaminics;*

3) Ointment with corticosteroid;*

4) Ointment with ichthyol;

5) Griseofulvin.

3. What factors simple dermatitis may be caused by?

1) Linen from synthetic fabric;

2) Low temperature;*

3) Ointments with antibiotics;

4) Detergents;

5) Sunbeams;*

6) Tight shoes.*

4. Which morphological elements of rash can’t appear in patients with simple dermatitis?

1) Macula;

2) Bulla;

3) Nodule;*

4) Papula;

5) Pustule;

6) Tubercle.*

5. What medicines toxicodermia may be caused by?

1) Ascorbic acid;

2) Sulphonamides;*

3) Dimedrol;

4) Aspirin;*

5) Prednisolone.

6. What is the uncorrect statement of toxicodermia?

1) Antigen is brought to the skin by hematogenous route;

2) Lesions have polymorphic character;

3) Eruptions regress after discontinue of entering of allergen into the skin;

4) The clinical picture of toxicodermia resembles the clinical picture of infectious diseases (measles, German measles, scarlet fever);

5) Mucous membrane of the mouth cavity is never affected.*

7. The followings lesions are distinguished in dermatitis, except:

1) Erythema;

2) Tubercle;*

3) Bulla;

4) Erosion;

5) Nodule;*

6) Papula.

8. Which lesions are characteristic for toxicodermia?

1) Macula (erythema);*

2) Macula (roseola);*

3) Hemorrhagic maculae;

4) Bulla;*

5) Vesicle;*

6) Nodule;

7) Ulcer;

8) Tubercle;

9) Papula.*

9. The clinical picture of Lyele’s toxicoallergic necrolysis is developed with the followings symptoms, except:

1) Temperature 38-40 °С;

2) Sickliness of skin coverings;

3) Headache and pain of skeletal and muscular system;

4) Nausea, vomitus, diarrhea;

5) Total itch;

6) ESR is not increased;*

7) Weakness.

10. The followings signs are distinguished in toxicodermia, except:

1) Roseola and erythema;

2) Papulae;

3) Temperature increases to 38-39 °С;

4) Tubercles and scars in the focus of affection;*

5) Burning pain in the focus of affection.

11. What etiological factors cause simple dermatitis?

1) The strong acids;*

2) The strong alkalis;*

3) Antibiotics;

4) Sulphonamides;

5) Foodstuff.

12. Which primary lesions can appear in patients with toxicodermia?

1) Maculae;*

2) Tubercle;

3) Papulae;*

4) Nodule;

5) Bullae.*

13. Which lesions are distinguished in allergic dermatitis:

1) Rozeola;*

2) Petechiae;

3) Vibex;

4) Erythema;*

5) Leucoderma;

6) Papulae;*

7) Bullae;*

8) Lichenification.

14. What external influences artificial dermatitis may be caused by?

1) Linen from synthetic fabric;

2) Low temperature;*

3) Tight shoes;*

4) Powdered detergents;

5) Using of 1-2% solution of brilliant green.

15. What external influences allergic dermatitis may be caused by?

1) Low temperature;

2) Low temperature with high humidity;

3) Antibiotics;*

4) Cosmetic;*

5) Products of distillation of petroleum;*

6) Rubber products.*

16. Artificial dermatitis is characterized:

1) Acute inflammation of a skin in the site of contact with irritant;*

2) Acute inflammation of a skin, outside the of contact with irritant;

3) Distinct borders of the focus of affection;*

4) Indistinct borders;

5) The rash always appears on the same place after repeated action of irritant.

17. What are the basic measures of preventive of drug toxicodermia?

1) Collection of allergic anamnesis;*

2) Preventive prescription of antihistaminics;*

3) Hypoallergic diet;*

4) Prescription of polyvitamins;

5) Prescription of antibiotics.

18. What factors can regard as obligate irritants?

1) The strong acids;*

2) The strong alkalis;*

3) Chemical warfare substances affecting the skin;*

4) Long-continued influence of unfavorable meteorological factors;*

5) Ointments with antibiotics.

19. Toxicodermia is characterized by:

1) Acute inflammatory reaction of the skin;

2) The process can extend to whole surface of the skin up to erythroderma;

3) Disorder of the general condition;

4) Fast regress of disease after elimination of allergen;

5) All listed above.*

20. A young man consulted to the dermatologist with the typical appearance of allergic dermatitis on his hands (hyperemia, edema, vesicles). These lesions appeared in 3 weeks since he began to work in cement factory. Which must be tactics of dermatologist with regard to this young man?

1) To release from work;*

2) To advise with specialist of occupational diseases;*

3) To prescribe antihistaminics;*

4) To prescribe vitamins;

5) To prescribe hyposensitization therapy.*

21. Which from following measures it is necessary to conduct in case of medicament toxicodermia due to oral administration of antibiotics?

1) To stop take antibiotics;*

2) Intake abundance of liquid;*

3) To prescribe of hyposensitization therapy;*

4) To prescribe of diuretic;*

5) To prescribe anti-inflammatory therapy externally.*

22. It is necessary to advise for patient with toxicodermia from tetracycline:

1) To change it on oletetrin;

2) To go on take tetracycline in smaller one-time dosage;

3) To stop take tetracycline;*

4) To prescribe antihistaminics;*

5) To prescribe hyposensitization therapy.*

23. What physical factors can cause simple dermatitis?

1) Mechanical influences;

2) Influence of high and low temperatures;

3) Various types of ray energy (penetrating and not penetrating radiation);

4) Influence of electric current;

5) All listed truly.*

24. It is necessary to advise for patient with allergic dermatitis from a powdered detergent:

1) To stop using a powdered detergent;*

2) Antihistaminics inside;*

3) Lotions for external treatment;*

4) Intravenous injection of 10 % calcium chloride;*

5) Preventive prescription of B complex vitamins.

25. The most widespread sensitizer are:

1) Polymers;

2) Salts of heavy metals;

3) Organophosphorous and organochlorine pesticides and insecticides;

4) Medicines;

5) All listed correct.*

26. In case of allergic contact dermatitis it is necessary to prescribe for external treatment:

1) Zinc paste;

2) Unna's cream;

3) Aqueous- zinc shake lotions;

4) Topical steroid hormone;*

5) 2 % salicylic acid cream.

27. What main principles of treatment and preventive of occupation allergic dermatosis do you know?

1) The discontinuation of contact to allergen;*

2) Changing the work;*

3) Prescription of external anti-inflammatory therapy;*

4) Prescription of hyposensitization therapy;*

5) Nothing from above listed.

28. Simple contact dermatitis is characterized by all signs except:

1) Clear-cut borders;

2) Localization in the places of contact with an irritant;

3) Appearance of wheals;*

4) Hyperemia;

5) Burning;

6) Appearance of tubercles.*

29. What substances have effect of photodynamic action:

1) Products of distillation of coal;

2) Products of distillation of oil;

3) Some medicines and plants;

4) Products of distillation of slates;

5) All listed truly.*

30. The characteristic signs of allergic dermatitis is/are:

1) Monovalent sensitization;*

2) Group sensitization;

3) Polyvalent sensitization;

4) Endogenous sensitization;*

5) Exogenous sensitization;*

6) Desensitization.

31. What is the most characteristic sign of allergic contact dermatitis?

1) It appears only in sensibilized persons to this irritant;*

2) There is polyvalent sensitization;

3) The area of inflammation depends on the concentration of irritant;

4) There is resistance to anti-inflammatory treatment.

32. In case of allergic contact dermatitis of hands due to powdered detergent it is necessary to prescribe:

1) To stop using a powdered detergent;

2) To eliminate the frequent washing of hands and using of other cleaning agent;

3) To prescribe inside Claritin;

4) To prescribe externally Flucinar;

5) All listed right.*

33. Which from the following medicines is the most effective in toxicodermia?

1) Wilkinson's ointment;

2) Unna's cream;

3) Celestoderm;*

4) Aqueous- zinc shake lotions;

5) 2 % salicylic acid ointment.

34. Name the stages of simple dermatitis:

1) Erythema;*

2) Vesicular and bullous eruptions;*

3) Necrotic-ulcerous;*

4) Oozing.

35. Name the signs of simple dermatitis:

1) The hidden period is present between the first contact with an irritant and appearance of dermatitis;

2) The degree of manifestation of dermatitis doesn’t correspond to strength of irritant;

3) The affection of a skin extends outside the place of contact with irritant;

4) The affection of a skin corresponds the site of contact with irritant.*

36. The clinical appearances of chronic dermatitis are:

1) Oozing;

2) Congested erythema;*

3) Erosions;

4) Infiltration, desquamation.*

LESSON 13


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