Subjects

The demographic characteristics of the subjects are listed in Table 1. There was a significant age differencebetween patients with schizophrenia and their relatives because the relativegroups included parents as well as siblings, and there was a greater proportionof men in the schizophrenia group. All subjects were of white ethnicity. Allpatients with schizophrenia were taking antipsychotic medication. Of the patientswith bipolar disorder, 31 were taking mood stabilizers, 1 was taking olanzapine,and 5 were receiving no medication. Unaffected relatives had never experienceda psychotic illness, but 10 relatives of patients with schizophrenia and 9relatives of patients with bipolar disorder had experienced another DSM-IV Axis 1 disorder at some point in their lives, mostlymajor depressive disorder. Four relatives of patients with schizophrenia alsofulfilled the criteria for schizotypal personality disorder.

Table Graphic Jump Location Table 1. Demographic Characteristics of Each Subject Group*

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