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The staff and children of a kindergarten are to be tested for meningococcal infection. Choose the method of microbiological research.

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  1. A child recovering from measles is diagnosed with pleuropneumonia. The disease is caused by conditional pathogenic Staphylococcus epidermidis. Name the type of infection.
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А. Skin allergic test.

В. Bacteriological.

C. Bacterioscopical.

D. Biological.

Е. Serological.

 

86. Gram - negative coffee bean shaped diplococci were found in the pyogenic discharge from the neck of uterus. They were located in leucocytes and outside them. They created a film in a fluid medium; they were inactive biochemically, produced endotoxin and could stimulate the inflammation of uterus. What agent caused the inflammation of the uterine neck?

А. Chlamydia trachomatis.

В. Haemophilus vaginalis.

C. Trichomonas vaginalis.

D. Neisseria gonorrhoeae.

Е. Calymmatobacterium granulomatis.

Bacteriologist followed all the rules during the research of a pathological material (cerebrospinal fluid, mucus from the pharynx, blood) because of high sensibility to environmental factors (low temperature) and to the demands of the celective media. Microscopy revealed Gram-negative coffee bean shaped cocci arranged in pairs or in tetrads. Name the isolated causative agent.

А. Neisseria meningitidis.

В. Staphylococcus aureus.

C. Neisseria gonorrhoeae.

D. Moraxella lacunata.

Е. Acinetobacter calcoaceticus.

88. During bacteriological investigation of the material taken from the patient suspected of chronic gonorrhoea no growth of microorganisms on special enriched media was observed. What method of diagnostics is to be used to confirm or deny the diagnosis of chronic gonorrhea?

А. Complement fixation test, skin allergic test with gonococcal antigen.

В. Determination of antibodies titre in patient’s blood serum using passive haemagglutination test.

C. Biological method.

D. Immune electrone microscopy.

Е. Reinvestigation of the material in differential-diagnostic medium.

 

89. Cerebrospinal fluid of a child suffering from cerebrospinal meningitis contained a great number of leucocytes. What serological reaction should be performed for express diagnostics of the disease?

А. Agglutination test.

В. Precipitation test.

C. Complement fixation test.

D. HAT (haemagglutination test).

Е. Neutralization test.

90. A child is suspected of pyogenic keratoconjuctivitis of ophthalmia neonatorum (gonococcal conjunctivitis, blennorrhea). What methods are most likely to confirm the diagnosis?

А. Microscopic and bacteriological.

В. Serological and skin allergic tests.

C. Biological and methods of bacteriophage typing.

D. Biological and skin allergic tests.

Е. Microscopic and serological.

 

91. A child suffering from nasal pharyngitis is diagnosed with meningococcal infectious disease. Which method of diagnostics is the most effective for the confirmation of diagnosis?

А. Biological test.

В. Serological.

C. Microscopic.

D. Bacteriological.

Е. Skin allergic test.

 

92. A patient is suspected of acute form of gonorrhea. Gram staining of the pus obtained from the urethra of the patient revealed a great number of cocci. What tinctorial properties and the way microorganisms are arranged in the preparation confirm this diagnosis?

А. Gram-positive cocci located in leucocytes and outside them.

В. Gram-positive diplococci located in leucocytes and outside them.

C. Gram-positive tetracocci located in leucocytes and outside them.

D. Gram-positive cocci arranged in chains.

Е. Gram-negative coffee-bean shaped diplococci located in leucocytes and outside them.

 

93. A patient who is known to have suffered from gonorrhea but recovered completely is diagnosed with acute gonorrhea again. What type of the disease is it?

А. Recurrence.

В. Secondary infection.

C. Reinfection.

D. Autoinfection.

Е. Superinfection.

 

94. There are some pathological processes associated with microbic factors: meningococcemia, acute pyelonephritis caused by Klebsiella, septic condition caused by Escherichia coli, bad wound infection caused by Proteus vulgaris and endometritis caused by enteroinfection of unknown origin. Name the common sign of these diseases.

А. Bacterial protein toxin intoxication.

В. Sepsis.

C. Intoxication caused by lypopolysaccharide endotoxin.

D. Presence of Gram-negative bacteria in blood.

Е. Septicemia with the development of allergic reactions.

 

95. Choose the condition which can ensure the right results in investigation of meningococcal infection:

А. Transportation of the material in cool condition

(t = 0-4,5 °C).

В. Transportation of the material in elective medium

(t = 37,5 °C, 1 hour).

C. Transportation of the material in preserving medium

(t = 20,5 °C).

D. Growth of the material obtained near the bed of the patient into MPB with protein.

Е. Transportation of the material in selective medium

(t = 37,5 °C, 1 hour).

 

96. Gram-negative diplococci located inside and outside leucocytes were identified in the preparation made from the patient’s cerebrospinal fluid which ran out under pressure during lumbar puncture. What is this disease called?

А. Blue pus bacillus.

В. Meningococcal infection.

C. Staphylococcal infection.

D. Tuberculosis.

Е. Pneumococcal infection.

 

97. A 5-year-old child presented with elevated body temperature up to 40 °C, headache, vomiting, anxiety, and chills. 4 days later hemorrhagic rash on the skin, olyguria, and suprarenal failure developed and it led to death. Meningococcus was determined during bacteriological research of pharyngeal smears. What type of disease was observed?

А. Meningococcemia.

В. Hydrocephaly.

C. Meningoencephalitis.

D. Meningococcal nasopharyngitis.

Е. Meningococcal meningitis.

 

98. Mother of a neonate visited an ophthalmologist of the outpatient department complaining of pyogenic discharge from the conjunctiva of the child’s eye. A great number of leucocytes and Gram-negative bean-shaped dyplococci were revealed inside leucocytes. What is the causative agent of the disease?

А. Streptococcus pyogenes.

В. Neisseria catarrhalis.

C. Staphylococcus epidermidis.

D. Neisseria gonorrhoeae.

Е. Staphylococcus aureus.

99. What is the most frequent reason of newborn bacterial meningitis?

А. Neisseria meningitidis.

В. Staphylococcus aureus.

C. Escherichia coli.

D. Streptococcus pyogenes.

Е. Streptococcus agalactiae.

100. A 30-year-old female suffers from chronic inflammation of the ovaries. Serological investigation by Bordet-Gengou reaction appeared to be positive. What microorganism is most likely to be the causative agent of the disease?

А. Neisseria gonorrhoеae.

В. Chlamydia trachomatis.

C. Treponema pallidum.

D. Ureаplasma ureаliticum.

Е. Trichomonas vaginalis.

101. Diagnostics of chronic gonorrhea by Bordet-Gengou reaction is performed in the bacteriological laboratory. Such reagents as gonococcal antigen, complement solution, hemolytic serum and erythrocyte suspension have been prepared. What is the function of complement in this reaction?

А. It is adsorbed on the complex "antigen-antibody".

В. It blocks nonspecific antibodies in the researched serum.

C. It is a part of hemolytic system.

D. Itrepresents itself as the indicator.

Е. It changes corpuscular antigen to soluble one.

 

102. Bacterioscopy of the sediment of cerebrospinal fluid of the patient suspected of meningitis revealed Gram-negative dyplococci. To confirm the diagnosis the sediment was inoculated on nutrient medium. What medium was used for the test?

А. Serum agar with rystomycin.

В. MPA with lincomycin.

C. Blood agar with penicillin.

D. Blood agar with lincomycin.

Е. MPA with rystomycine.

 

103. Pathologic material (pyogenic discharge from the urogenital system of the patient diagnosed with acute urethritis) was delivered to the bacteriological laboratory. To separate the causative agent the nutrient medium of serum agar with vancomycin and nystatin was prepared. What microorganism is likely to be isolated by bacteriologist?

А. Gonococcus.

В. Treponema pallidum.

C. Candida genus fungus.

D. Chlamydia.

Е. Staphylococcus aureus.

 

104. A young female unexpectedly developed high body temperature up to 39 °C and bad headache. On examination, a physician observed rigidity of occipital muscles and administered lumbar puncture. Gram staining of the preparation made from the cerebrospinal fluid revealed a great number of neutrophils and Gram-negative dyplococci. What species of bacteria caused the disease?

А. Neisseria meningitidis.

В. Streptococcus pneumoniaе.

C. Haemophilus inluenzae.

D. Staphylococcus aureus.

Е. Pseudomonas aeruginosa.

105. A child from the kindergarten is diagnosed with meningococcal nasal pharingitis. What type of vaccine will be administered to the other children for immediate specific prophylaxis of meningococcal infection?

А. Chemical.

В. Attenuated (live).

C. Inactivated.

D. Toxoid.

Е. Mixed vaccine.

 

106. Microscopy of the pus swab revealed a great number of Gram-negative cocci. What nutrient medium is used for bacteriological investigation of the pus?

А. Blood agar.

В. MPA.

C. Endo agar.

D. Bile broth.

Е. MPAwithbile.

 

107. A culture of meningococcus was isolated from the sediment of the cerebrospinal fluid of the patient diagnosed with meningitis. What serological reaction is to be performed to determine the serum group of the causative agent?

А. AT.

В. PT.

C. PHAT.

D. CFT.

Е. Reaction of immune lysis.

 

108. A neonate was born without medical assistance, not in the maternity hospital. During pregnancy the mother was not checked up properly. On the second day a newborn was hospitalized with acute purulent conjunctivitis. Microscopy of the discharge from the eyes of the baby revealed Gram-negative diplococci settled inside and outside leucocytes. What microorganism is likely to be the causative agent of the disease?

А. Neisseria gonorrhoеae.

В. Chlamydia trachomatis.

C. Corynebacterium diphtheriae.

D. Staphylococcus aureus.

Е. Pseudomonas aeruginosa.

109. In the mucus of the rhinopharynx bacteriologist revealed small pair settled bean shaped microorganisms. Gram staining changed pigmentation to pink color. What microorganisms were revealed by bacteriologist?

А. Neisseria.

В. Staphylococci.

C. Streptococci.

D. Enterococci.

Е. Micrococci.

110. A sick doctor is diagnosed with gonorrhea. What method of microbiological diagnostics was used by bacteriologist to confirm the diagnosis?

А. Microscopic (microscopy of pathological material).

В Biological (infected laboratory animals).

C. Bacteriological (test with bacteriophage).

D. Serological (hemagglutination reaction).

Е. Serological (immobilization reaction).


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