germ cell tumor, hepatocellular carcinoma

Tumor marker	Associated tumor types
Alpha fetoprotein(AFP)	germ cell tumor, hepatocellular carcinoma
CA15-3	breast cancer
CA27-29	breast cancer
CA19-9	Mainly pancreatic cancer, but also colorectal cancer and other types ofgastrointestinal cancer.
CA-125	Mainly ovarian cancer, but may also be elevated in for example endometrial cancer, fallopian tube cancer, lung cancer, breast cancer and gastrointestinal cancer. May also increase in endometriosis.
Calretinin	mesothelioma, sex cord-gonadal stromal tumour, adrenocortical carcinoma, synovial sarcoma
Carcinoembryonic antigen (CEA)	gastrointestinal cancer, cervix cancer, lung cancer, ovarian cancer, breast cancer,urinary tract cancer
CD34	hemangiopericytoma/solitary fibrous tumor, pleomorphic lipoma, gastrointestinal stromal tumor, dermatofibrosarcoma protuberans
CD99	Ewing sarcoma, primitive neuroectodermal tumor, hemangiopericytoma/solitary fibrous tumor, synovial sarcoma, lymphoma, leukemia, sex cord-gonadal stromal tumour
CD117	gastrointestinal stromal tumor, mastocytosis, seminoma
Chromogranin	neuroendocrine tumor
Cytokeratin(various types)	Many types of carcinoma, some types of sarcoma
Desmin	smooth muscle sarcoma, skeletal muscle sarcoma, endometrial stromal sarcoma
Epithelial membrane protein (EMA)	many types of carcinoma, meningioma, some types of sarcoma
Factor VIII, CD31FL1	vascular sarcoma
Glial fibrillary acidic protein(GFAP)	glioma (astrocytoma, ependymoma)
Gross cystic disease fluid protein (GCDFP-15)	breast cancer, ovarian cancer, salivary gland cancer
HMB-45	melanoma, PEComa (for example angiomyolipoma), clear cell carcinoma,adrenocortical carcinoma
Human chorionic gonadotropin(hCG)	gestational trophoblastic disease, germ cell tumor, choriocarcinoma
immunoglobulin	lymphoma, leukemia
inhibin	sex cord-gonadal stromal tumour, adrenocortical carcinoma, hemangioblastoma
keratin (various types)	carcinoma, some types of sarcoma
PTPRC (CD45)	lymphoma, leukemia, histiocytic tumor
lymphocyte marker (various types	lymphoma, leukemia
MART-1 (Melan-A)	melanoma, steroid-producing tumors (adrenocortical carcinoma, gonadal tumor)
Myo D1	rhabdomyosarcoma, small, round, blue cell tumour
muscle-specific actin (MSA)	myosarcoma (leiomyosarcoma, rhabdomyosarcoma)
neurofilament	neuroendocrine tumor, small-cell carcinoma of the lung
neuron-specific enolase (NSE)	neuroendocrine tumor, small-cell carcinoma of the lung, breast cancer
placental alkaline phosphatase(PLAP)	seminoma, dysgerminoma, embryonal carcinoma
prostate-specific antigen	prostate
S100 protein	melanoma, sarcoma (neurosarcoma, lipoma, chondrosarcoma), astrocytoma,gastrointestinal stromal tumor, salivary gland cancer, some types ofadenocarcinoma, histiocytic tumor (dendritic cell, macrophage)
smooth muscle actin (SMA)	gastrointestinal stromal tumor, leiomyosarcoma, PEComa
synaptophysin	neuroendocrine tumor
thyroglobulin	thyroid cancer (but not in medullary thyroid cancer)
thyroid transcription factor-1	all types of thyroid cancer, lung cancer
Tumor M2-PK	colorectal cancer, Breast cancer, renal cell carcinoma, Lung cancer, Pancreatic cancer, Esophageal Cancer, Stomach Cancer, Cervical Cancer, Ovarian Cancer.
vimentin	sarcoma, renal cell carcinoma, endometrial cancer, lung carcinoma, lymphoma,leukemia, melanoma

Дата добавления: 2015-11-04