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More often diabetes mellitus occurs at:



?

More often diabetes mellitus occurs at:

+children of the school age

-3-5 years old children

-first year of life children

-teenagers

-newborns

?

Diabetes mellitus is a result of:

+autoimmune destruction of beta- cells

-mono-viremia

-hyperplasia of pancreas

-hypothyroidism

-hyperthyroidism

?

Early signs of insulin insufficiency are:

+hyperglycemia after food

-hyperglycemia fasting

-ketoacidosis

-lactateacidosis

-hypoglycemia

?

Insulin deficit causes:

+gluconeogenesis

-using of glucose

-increase of glycogen synthesis

-absence of gluconeogenesis

-decrease of glycogen synthesis

?

Point the signs of anabolism of insulin in liver, muscles and fat tissue:

+lipogenesis

-glycogenolysis

-gluconeogenesis

-lipolysis

-ketogenesis

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Contr- insular hormones include:

+glucagon

-calcitonin

-antidiuretic hormone

-parathormone

-thyrotropic hormone

?

Contr-insular hormones include everything, except the following:

-glucagon

-somatotropic hormone

-catecholamine

+parathormone

-glucocorticoids

?

Point the right statement:

+adrenalin furthers the decrease of insulin synthesis

-contr-insular hormones conduce utilization and elimination of glucose

-glucosuria occurs in case of decrease of glucagon and antidiuretic hormone level

-adrenalin conduces increase of insulin synthesis

-adrenalin furthers decrease of glucagon decay

?

Glucosuria occurs when the glucose level in serum is:

+>10,2 mkmol/l

->7,8 mkmol/l

-<20,5 mkmol/l

->25 mmol/l

-5 mmol/l

?

Hyperglycemia causes:

+ hyperosmolarity of plasma and urine

- hyperosmolarity of plasma and hyposmolarity of urine

- hyposmolarity of plasma and hyperosmolarity of urine

- hyposmolarity of plasma and urine

-hyposmolarity of plasma and liquor

?

Clinical symptoms of diabetes mellitus are:

+polyuria

-overweight

-skin pallor

-temperature increase

- skin itch

?

Diagnosis of diabetes mellitus is determined on the base of:

+glucosuria

-hypoglycemia

-disproteinemia

-acidosis

-leucocytosis

?

Point the symptoms that are typical for diabetes mellitus:

+loosing weight

-bad appetite

-fructosuria

-eczema

-anemia

?

Point signs of “violations of tolerance to glucose”:

+absence of hyperglycemia fasting

-hyperglycemia fasting

-glucosuria

-normal level of glucose in 2 hours after food

-increase of level of glucolazed hemoglobin

?

Point child’s need in insulin on the early stages of diabetes mellitus:

+0,5 UA/kg/day

-0,75-0,8 UA/kg/day

-0,75-1 UA/kg/day

-0,1-0,2 UA/kg/day

-5 UA/kg/day

?

Point the correlation of daily and night doses of insulin in case of diabetes mellitus:

+2:1

-1:2

-1:3

-3:1

-4:1

?

Point the daily need in insulin in case of developed diabetes mellitus:

+0,75-1,0 UA/kg

-0,5-0,75 UA/kg

-0,1-0,5 UA/kg

-1,5-2,0 UA/kg

-5-7 UA/kg

?

Point the insulin preparations of the short activity:

+SU-insulin

-homofan

-insulin Lente

-ultralente

-insulong

?

Point the insulin preparations of medium activity:

-homorap

-ultralente

-SU- insulin

+insulin Lente

-ultratard

?

What is the insulin preparation of prolonged activity:

+ultralente

-homorap

-insulin Lente

-SU-insulin

-insulong

?

Determine the regime of insulin injection:

+regime corresponds to physiologic insulin secretion

-insulin is injected in 30 min after every food taking

-regime of insulin injection is determined by the need in it

-insulin is injected in 60 min after every food taking

-regime of insulin injection does not have sense

?

The highest hyperglycemia is characteristic for:

+hyperosmolar coma

-ketoacidotic coma

-lactateacidotic coma

-hypoglycemic coma

-hepatic coma

?

Convulsions are the most typical for development of:

-hyperosmolar coma

-ketoacidotic coma

-lactateacidotic coma

+hypoglycemic coma

-hepatic coma

 

?

Presence of ketone bodies +++ in urine is characteristic for:

-hyperosmolar coma

+ketoacidotic coma

-lactateacidotic coma

-hypoglycemic coma

-hepatic coma

 

?

Gradual beginning and development of coma is characteristic for:



-hyperosmolar coma

+ketoacidotic coma

-lactateacidotic coma

-hypoglycemic coma

-hepatic coma

?

Increased level of K in blood serum is typical for:

-hyperosmolar coma

+ketoacidotic coma

-lactateacidotic coma

-hypoglycemic coma

-hepatic coma

?

Saved diuresis is characteristic for:

-hyperosmolar coma

-ketoacidotic coma

-lactateacidotic coma

+hypoglycemic coma

-hepatic coma

?

There is no need in glucose- tolerant test holding, if:

+repeated glucose level in blood serum fasting is higher then 7 mmol/l and there is clinical signs of diabetes mellitus

- glucose level in blood serum fasting is higher then 6 mmol/l and there is one absolute criteria of risk of diabetes mellitus development

- glucose level in blood serum fasting is higher then 7 mmol/l and there are two criteria of relative risk of pancreatic diabetes development

- glucose level in blood serum fasting is higher then 5 mmol/l and there is one criteria of relative risk of pancreatic diabetes development

- repeated glucose level in blood serum fasting is higher then 4 mmol/l and there is clinical signs of diabetes mellitus

 

?

"Objective" criteria of pancreatic diabetes is:

+hyperglycemia higher then 8,8 mkmol/l and glucosuria

- hyperglycemia higher then 6 mkmol/l and glucosuria

 

- hyperglycemia higher then 8,8 mkmol/l and ketonuria

- hyperglycemia higher then 8,8 mkmol/l and ketonemia

- hyperglycemia higher then 6 mkmol/l and ketonuria

 

?

Negative glucose- tolerant test includes the next criteria of assessment, except the following:

-maximal sugar level in 60 min after load should not be higher than starting one by more then 50%

-in 120 min maximal sugar level should reduces to the starting one

-there is no glucosuria ever

- in 120 min maximal sugar level should be lower than the starting one

+ in 120 min maximal sugar level should not be higher the starting one by more then 50%

?

Absolute criteria of risk of PD development include everything, except the following:

+obesity

-one of the twins has PD

-mother is sick, father has sick relatives

-father is sick, mother has sick parents

?

Relative criteria of risk of PD development include everything, except the following:

+increased content of glycolized hemoglobin

-obesity

-pancreatic diseases

-periodical hyperglycemia

-prolonged usage of glucocorticoids

?

14-year old boy with PD (134 sm- height, 64 kg- body weight) – has hepatomegalia, retardation of sexual development. Hypoglycemic states are often for this patient. What PD complication does the patient have?

-Kushing syndrome

-liver cirrhosis

+Moriak syndrome

-somatogenic nanism

-chronic hepatitis

?

5-year old child complains on the total weakness, sense of hunger, thirst. He is backwards in the physical development, there are signs of dehydration. Polyuria, glucosuria (more than 2 g per day). Members of family have benign glucosuria. What is the most possible diagnosis?

-pancreatic diabetes

-penthosuria

-kidney glucosuria

-fructosuria

-tubular necrosis

?

At 9-year old child pancreatic diabetes was determined at the first time. What will be the most possible way of visualization of skin damages?

+inclination to purulent diseases

-depigmentation

-hyperpigmentation

- elephantiasis development

-petechias

?

Mother of 6-year old child mentions that last 2 weeks the child always goes to bathroom for few times during night, drinks water a lot, that he lost some weight, periodically he complains on the stomach ache. Objectively: skin is pale, dry, there is desquamation on feet, and blush on cheeks. Lips and tongue are bright red color, dry. Internals are without features. There is smell of acetone from mouth. Glycemia is 12 mmol/l. The diagnosis of diabetes mellitus is determined. What therapy is the most appropriate at the soonest time?

-biguanids

-diet- therapy

-insulin of medium activity

+simple insulin

-insulin of prolonged activity

?

10-year old boy was hospitalized with polyuria, polydipsia, loosing weight during last 3 month at 25 %. During examination glycemia – 16 mmol/l, acetone in urine (+++) were determined. Pancreatic diabetes was diagnosed at the first time. What the daily dose of insulin should be prescribed?

-0,1 UA/kg by 1 hour.

-1 UA/kg

-2 UA/kg

-0,25 UA/kg

+0,5 UA/kg

?

Parents of the 7-year old boy came to doctor with complains on: during last 2-3 weeks child had polyuria, thirst, weight loose down to 4 kg. Objectively: skin is pale, dry, tissue turgor is decreased, there is smell of acetone from mouth. What diagnosis is the most possible?

-acetonemic syndrome

- diabetes insipidus

-kidney diabetes

+pancreatic diabetes

-Alport’s syndrome

?

Point permissible content of ketone bodies in the blood serum:

+ up to 1,72 mmol/l

-up to 0,72 mmol/l

-up to 2,72 mmol/l

-up to 5,2 mmol/l

-up to 3,25 mmol/l

?

Point the permissible content of glucose in urine:

+up to 1,1 mmol/l

-up to 10,1 mmol/l

-up to 110 mmol/l

-up to 0,5 mmol/l

-up to 5,2 mmol/l

?

Point the normal level of K in the blood serum:

+4,0-5,5 mmol/l

-1,5-3,0 mmol/l

-6,0-7,5 mmol/l

-8,0-11,5 mmol/l

-0,2-1,0 mmol/l

?

Point the normal level of Na in the blood serum:

+135-145 mmol/l

-150-160 mmol/l

-110-125 mmol/l

-65-80 mmol/l

-30-50 mmol/l

?

Point the dose of glucagon in case of difficult glycemia for 5-year old child:

+0,5 mg

-0,2 mg

-1 mg

-5 mg

-0,1 mg

 

?

Point the dose of glucagon in case of difficult glycemia for child older then 5 years:

-0,5 mg

-0,2 mg

+1 mg

-5 mg

-0,1 mg

 

?

Point the dose of glucose in case of difficult glycemia:

+1 ml/kg of 20% solution

-5 ml/kg of 20% solution

-1 mg/kg of 20% solution

-0,1 mg/kg of 10% solution

-0,5 ml/kg of 20% solution

?

Point the dose of insulin at treatment of diabetic ketoacidosis:

+0,1 UA/kg/hour

-0,1 UA/kg/min.

-0,1 UA/kg

-0,5 U/kg

-1 UA/kg/hour

?

Point the normal level of K in erythrocytes:

+80-100 mmol/l

-40-60 mmol/l

-120-140 mmol/l

-60-80 mmol/l

-160-200 mmol/l

?

Point the normal level of Na in erythrocytes:

+12-25 mmol/l

-5-10 mmol/l

-30-45 mmol/l

-1-8 mmol/l

-50-65 mmol/l

?

Point the normal level of lactic acid in the blood serum:

+0,4-1,4 mmol/l

-0,2-0,3 mmol/l

-1,5-1,8 mmol/l

-2,0-2,5 mmol/l

-2,6-4,0 mmol/l

?

The best method to prevent hypoglycemia development is:

+conversion on plural insulin injection

-decrease of insulin dose at its single injection

?

Insulin is not used at treatment of:

+hypoglycemic coma

-ketoacidotonic coma

-lactate coma

-hyperosmolar coma

-hepatic coma

?

For treatment of hyperosmolar coma next preparations, except the following are used:

+ sodium bicarbonate

-insulin

-3% glucose solution

-potassium chloride

?

The level of glycolized hemoglobin that shows the compensation of pancreatic diabetes is:

+less then 6,5%

-less then 8,5%

-more then 10,5%

-it does not matter

-more then 15,5%

?

Cholesterol level that shows the compensation of pancreatic diabetes is:

+less then 5,2 mmol/l

-less then 6,6 mmol/l

-less then 8,8 mmol/l

-less then 8,2 mmol/l

-less then 6,0 mmol/l

?

Missing the insulin injection causes the development of:

+diabetic ketoacidosis

-hypoglycemic coma

-lactateacidotic coma

-hyperosmolar coma

-hepatic coma

?

Overdose of insulin causes the development of:

+hypoglycemia

-diabetic ketoacidosis

-lactateacidotic coma

-hyperosmolar coma

-hepatic coma

 

?

What are the early complications of pancreatic diabetes:

+hypoglycemic coma

-diabetic nephropathy

-diabetic retinopathy

-diabetic neuropathy

-all the answers are correct

?

What is basic- ballast therapy of pancreatic diabetes:

+usage of insulin of short and prolonged activity in correlation 1:1

- usage of insulin of medium and short activity in correlation 2:1

- usage of insulin of prolonged and medium activity in correlation 1:1

- usage of insulin of short and medium activity in correlation 3:1

-usage of insulin of prolonged activity

?

Urgent hospitalization and parenteral injection of glucagon and glucose is necessary in case of:

+difficult hypoglycemia

-light hypoglycemia

-moderate hypoglycemia

-all the answers are correct

 

 


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